Firewall and Antivirus - Make sure SimCity.exe and Origin.exe are added to exception lists. If you have BitDefender installed, disable it.
Graphics drivers and Windows OS are patched and updated to newest versions
SimCity.exe and Origin.exe - Set them to run "as administrator"
Nahimic 2 from MSI - this is an audio management program that comes with MSI motherboards. Disable or uninstall it. Nahimic 2 is known to cause this issue.
If you get stuck during the installation again, close out of Origin completely.
Copy update files to SimCity folder. Go to Program Files (x86)\Origin Games\SimCity\SimCityUserData\Patches\UpdatedApp Select all files (Ctrl-A) and copy (Ctrl-C). Go to \Program Files (x86)\Origin Games\SimCity and paste (Ctrl-V). Choose to overwrite any files that already exist.
Definitely post back and let us know whether something worked, and any error messages you might have. Happy building!